100 trials changed in the last 30 days: 3 stopped, 62 with notable changes, 35 with minor changes only.
Withdrawn before enrolling
Sponsor's reason: No funding.
Also in this update: Primary completion pushed from Jan 1, 2028 to Oct 5, 2028; Study completion moved earlier from Jan 1, 2029 to Oct 5, 2028
Mayo ClinicNot applicable NCT06891001 Registry history of NCT06891001 on ClinicalTrials.gov (opens the registry)
Updated
Trial status changed: Recruiting → Withdrawn
Sponsor's reason: Unable to start study.
Mayo ClinicPhase 4 NCT04730609 Registry history of NCT04730609 on ClinicalTrials.gov (opens the registry)
Updated
Trial terminated
Sponsor's reason: Slow accrual; lack of eligible study participants
Also in this update: Final enrollment: 11 participants (planned 24); Primary completion date changed from estimate of May 1, 2028 to Jul 29, 2026
Mayo ClinicNot specified NCT05575440 Registry history of NCT05575440 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Jul 2029 to Sep 30, 2030
Also in this update: Enrollment closed, study ongoing
Mayo ClinicPhase 2 NCT04858009 Registry history of NCT04858009 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Aug 31, 2026 to Aug 31, 2028
Also in this update: Study completion pushed from Aug 31, 2029 to Aug 31, 2031
Mayo ClinicEarly Phase 1 NCT05045066 Registry history of NCT05045066 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Dec 2026 to Aug 2028
Mayo ClinicPhase 3 NCT06693674 Registry history of NCT06693674 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Oct 1, 2026 to Jun 1, 2027
Mayo ClinicNot applicable NCT07040397 Registry history of NCT07040397 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Aug 30, 2026 to Apr 30, 2027
Also in this update: Study completion pushed from Aug 30, 2031 to Apr 30, 2032
Mayo ClinicNot applicable NCT06325046 Registry history of NCT06325046 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Sep 2026 to Mar 2028
Mayo ClinicNot applicable NCT05923359 Registry history of NCT05923359 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Nov 30, 2026 to Dec 30, 2027
Mayo ClinicPhase 3 NCT06395441 Registry history of NCT06395441 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Dec 31, 2026 to Dec 31, 2027
Also in this update: Study completion pushed from Dec 31, 2026 to Dec 31, 2028
Mayo ClinicPhase 1/2 NCT06704191 Registry history of NCT06704191 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Jan 15, 2027 to Jan 2028
Also in this update: Study completion pushed from May 31, 2027 to Jul 2028
Mayo ClinicPhase 2/3 NCT07487818 Registry history of NCT07487818 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Dec 31, 2027 to Apr 23, 2029
Mayo ClinicPhase 2 NCT06639074 Registry history of NCT06639074 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Nov 10, 2026 to Jul 19, 2028
Mayo ClinicPhase 2 NCT06153836 Registry history of NCT06153836 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from May 30, 2027 to May 25, 2029
Mayo ClinicPhase 2 NCT06078709 Registry history of NCT06078709 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Apr 29, 2027 to Dec 2, 2030
Also in this update: Study completion pushed from Apr 29, 2027 to Dec 2, 2033
Mayo ClinicPhase 2 NCT06918132 Registry history of NCT06918132 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Aug 1, 2028 to Sep 6, 2029
Also in this update: Study completion pushed from Aug 1, 2029 to Sep 6, 2029
Mayo ClinicPhase 2 NCT05541016 Registry history of NCT05541016 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Jun 30, 2028 to Aug 5, 2029
Mayo ClinicPhase 2 NCT06997068 Registry history of NCT06997068 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Nov 30, 2026 to Nov 30, 2029
Also in this update: Study completion pushed from Nov 30, 2026 to Nov 30, 2031
Mayo ClinicPhase 2 NCT05898646 Registry history of NCT05898646 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Jan 30, 2027 to Jul 30, 2027
Mayo ClinicPhase 2 NCT05557877 Registry history of NCT05557877 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Also in this update: Final enrollment: 3 participants (planned 20)
Mayo ClinicPhase 2 NCT06660407 Registry history of NCT06660407 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Primary completion date changed from estimate of Dec 30, 2027 to Feb 23, 2026
Mayo ClinicNot applicable NCT06037863 Registry history of NCT06037863 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Final enrollment: 30 participants (planned 50); Primary completion date changed from estimate of Apr 24, 2027 to Jul 30, 2025
Mayo ClinicNot specified NCT06901284 Registry history of NCT06901284 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Primary completion date changed from estimate of Jul 30, 2030 to Nov 25, 2025
Mayo ClinicNot applicable NCT03961945 Registry history of NCT03961945 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Also in this update: Primary completion date changed from estimate of Oct 15, 2027 to Sep 2, 2026; Study completion pushed from Oct 15, 2028 to Sep 2, 2031
Mayo ClinicPhase 2 NCT05465954 Registry history of NCT05465954 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Also in this update: Primary completion date changed from estimate of Feb 22, 2027 to Sep 23, 2026; Study completion pushed from Feb 22, 2027 to Mar 30, 2031
Mayo ClinicPhase 2 NCT05388006 Registry history of NCT05388006 on ClinicalTrials.gov (opens the registry)
Updated
Trial status changed: Enrolling by Invitation → Active, Not Recruiting
Mayo ClinicNot applicable NCT07098715 Registry history of NCT07098715 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Primary completion date changed from estimate of Sep 2026 to Jul 17, 2026
Mayo ClinicNot applicable NCT05968859 Registry history of NCT05968859 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Also in this update: Primary completion moved earlier from May 1, 2027 to Feb 1, 2027; Study completion pushed from May 1, 2027 to Feb 1, 2028
Mayo ClinicPhase 2 NCT06377696 Registry history of NCT06377696 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Also in this update: Primary completion date changed from estimate of Oct 1, 2027 to Aug 17, 2026; Study completion moved earlier from Oct 1, 2028 to Feb 17, 2027
Mayo ClinicPhase 1/2 NCT04605913 Registry history of NCT04605913 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Also in this update: Study completion pushed from Aug 31, 2026 to Oct 31, 2026
Mayo ClinicPhase 4 NCT07221617 Registry history of NCT07221617 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Mayo ClinicNot applicable NCT05525845 Registry history of NCT05525845 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Final enrollment: 62 participants (planned 69); Primary completion date changed from estimate of Sep 8, 2026 to Jun 8, 2026
Mayo ClinicNot applicable NCT04493372 Registry history of NCT04493372 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Aug 1, 2028 to Nov 1, 2028
Mayo ClinicPhase 2 NCT07612007 Registry history of NCT07612007 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from May 31, 2030 to Aug 31, 2030
Also in this update: Study completion moved earlier from Feb 28, 2031 to Aug 31, 2030
Mayo ClinicPhase 1/2 NCT03942328 Registry history of NCT03942328 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Sep 1, 2026 to Jan 1, 2027
Mayo ClinicNot applicable NCT06424015 Registry history of NCT06424015 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Dec 31, 2026 to May 1, 2027
Mayo ClinicPhase 2 NCT06265285 Registry history of NCT06265285 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Mar 3, 2027 to Jun 10, 2027
Also in this update: Study completion pushed from Mar 3, 2027 to Sep 9, 2028
Mayo ClinicPhase 2 NCT06834373 Registry history of NCT06834373 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Feb 15, 2027 to Aug 1, 2027
Also in this update: Study completion moved earlier from Feb 15, 2028 to Aug 1, 2027
Mayo ClinicPhase 2 NCT05222620 Registry history of NCT05222620 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Apr 30, 2029 to Sep 1, 2029
Also in this update: Study completion moved earlier from Apr 30, 2034 to Sep 1, 2032
Mayo ClinicPhase 2 NCT07301268 Registry history of NCT07301268 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Sep 26, 2028 to Dec 21, 2028
Also in this update: Study completion moved earlier from Sep 26, 2029 to Jun 21, 2029
Mayo ClinicPhase 2 NCT07460752 Registry history of NCT07460752 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Dec 18, 2026 to May 15, 2027
Mayo ClinicPhase 2 NCT07285044 Registry history of NCT07285044 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Aug 30, 2026 to Dec 31, 2026
Mayo ClinicNot applicable NCT07006142 Registry history of NCT07006142 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Sep 30, 2026 to Dec 15, 2026
Mayo ClinicNot specified NCT06880861 Registry history of NCT06880861 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Sep 1, 2026 to Jan 1, 2027
Mayo ClinicNot applicable NCT06045962 Registry history of NCT06045962 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion date changed from estimate of Sep 1, 2026 to Mar 2, 2026
Also in this update: Study completion moved earlier from May 1, 2031 to Sep 2, 2030
Mayo ClinicPhase 2 NCT04607954 Registry history of NCT04607954 on ClinicalTrials.gov (opens the registry)
Updated
Study completion pushed from Sep 13, 2026 to Dec 13, 2026
Mayo ClinicNot applicable NCT06329557 Registry history of NCT06329557 on ClinicalTrials.gov (opens the registry)
Updated
Study completion pushed from Sep 10, 2026 to Jan 10, 2027
Mayo ClinicPhase 1/2 NCT05232851 Registry history of NCT05232851 on ClinicalTrials.gov (opens the registry)
Updated
Study completion pushed from Sep 2026 to Jan 2027
Mayo ClinicPhase 2 NCT04868838 Registry history of NCT04868838 on ClinicalTrials.gov (opens the registry)
Updated
Interventions modified
Mayo ClinicPhase 2 NCT03418038 Registry history of NCT03418038 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion moved earlier from Sep 15, 2027 to Mar 15, 2027
Also in this update: Study completion pushed from Sep 15, 2027 to Mar 15, 2028
Mayo ClinicPhase 1 NCT05030298 Registry history of NCT05030298 on ClinicalTrials.gov (opens the registry)
Updated
Start date changed from estimate of Aug 24, 2026 to Sep 1, 2026
Mayo ClinicNot applicable NCT07817706 Registry history of NCT07817706 on ClinicalTrials.gov (opens the registry)
Updated
Study completion pushed from Aug 2026 to Aug 2027
Mayo ClinicNot specified NCT05353478 Registry history of NCT05353478 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion date changed from estimate of Aug 2026 to Jun 5, 2026
Mayo ClinicNot specified NCT07455370 Registry history of NCT07455370 on ClinicalTrials.gov (opens the registry)
Updated
Study completion moved earlier from Jun 2027 to Feb 23, 2027
Mayo ClinicNot specified NCT07772817 Registry history of NCT07772817 on ClinicalTrials.gov (opens the registry)
Updated
| First posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-10-15 | NCT07874841 Varenicline for Smoking Cessation in Pancreatitis | Phase 4 | Not Yet Recruiting |
| 2026-10-09 | NCT07868614 Intraoperative Microelectrode Recordings Using MAVEN Compared to Standard Recording… | Recruiting | |
| 2026-10-07 | NCT07862205 EEG-Guided Transcranial Magnetic Stimulation for Adults With Depression | Not Yet Recruiting | |
| 2026-10-02 | NCT07856394 Adding Spatially Fractionated Radiation Therapy to Standard Palliative Radiation for… | Recruiting | |
| 2026-09-30 | NCT07850284 SMS-Based Remote Symptom Monitoring for Patients With Plasma Cell Disorders | Recruiting | |
| 2026-09-28 | NCT07843420 Nemolizumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus | Phase 2 | Not Yet Recruiting |
| 2026-09-24 | NCT07838324 A Pilot Investigation of Pain Reprocessing Therapy for Functional Dyspepsia | Recruiting | |
| 2026-09-24 | NCT07840144 Lower Body Negative Pressure to Validate Physiological Monitors | Recruiting | |
| 2026-09-22 | NCT07835295 REMIfentanil (2 vs. 4 mcg/kg) Facilitated Intubation Without Neuromuscular Blockade… | Phase 4 | Not Yet Recruiting |
| 2026-09-21 | NCT07829692 Effectiveness of an 8-week Independent Cadence Retraining Program on Stress Urinary… | Recruiting |
| Early Phase 1 | 19 | |
| Phase 1 | 37 | |
| Phase 1/2 | 17 | |
| Phase 2 | 107 | |
| Phase 2/3 | 3 | |
| Phase 3 | 12 | |
| Phase 4 | 51 |
| NCT ID | Title | Condition | Status | Updated |
|---|---|---|---|---|
| Phase 4 | ||||
| NCT07218445 | The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in… | Obesity | Recruiting | 2026-10-06 |
| NCT06764095 | Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally… | Locally Advanced Bladder Urothelial Carcinoma | Recruiting | 2026-10-01 |
| NCT07164131 | Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired… | Community-acquired Pneumonia | Recruiting | 2026-09-24 |
| NCT07424625 | A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac… | Metabolic Acidosis | Recruiting | 2026-09-21 |
| NCT05856136 | A Study to Investigate the Effects of Opioid Exposure on the Ability of the Diaphragm… | Respiratory Function Loss | Recruiting | 2026-09-17 |
| NCT06401642 | Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those… | Migraine | Recruiting | 2026-09-17 |
| NCT06972056 | Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study | Migraine | Recruiting | 2026-09-16 |
| NCT05285566 | Pain Control for Undergoing Costal Cartilage Harvesting | Nasal Surgery | Recruiting | 2026-09-11 |
| NCT07632820 | Erector Spinae Plane Block Versus Trigger Point Injection for Chronic Thoracic Myofascial… | Back Pain | Recruiting | 2026-09-09 |
| NCT07283497 | Itraconazole Therapy In Bronchiectasis With Airway Mold | Bronchiectasis | Recruiting | 2026-08-21 |
| NCT07594535 | The Effect Of Lisinopril On Polycythemia | Polycythemia | Recruiting | 2026-08-21 |
| NCT06832878 | Postoperative Oral Tranexamic Acid in Patients Undergoing Primary Total Joint Arthroplasty | Arthroplasty | Recruiting | 2026-08-10 |
| NCT07285863 | A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid… | Exocrine Pancreatic Insufficiency | Recruiting | 2026-07-07 |
| NCT07174349 | Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative… | Urinary Retention Postoperative | Recruiting | 2026-06-29 |
| NCT07266545 | RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression… | Unipolar Depression | Recruiting | 2026-06-22 |
| NCT05837091 | Low Sodium Oxybate in Patients With Idiopathic Hypersomnia | Idiopathic Hypersomnia | Recruiting | 2026-05-12 |
| NCT07325240 | 24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular… | Open Angle Glaucoma | Recruiting | 2026-05-01 |
| NCT07217405 | Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis | Osteoarthritis Hand | Recruiting | 2026-04-24 |
| NCT06568549 | Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC… | Kidney Transplantation | Recruiting | 2026-03-20 |
| NCT07213466 | Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder | Bipolar I Disorder | Recruiting | 2026-03-11 |
| NCT06782529 | Knee Injections for Obese Patients With Knee Arthritis | Osteoarthritis of Knee | Recruiting | 2026-03-10 |
| NCT06525740 | Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic… | Malignant Female Reproductive System Neoplasm | Recruiting | 2026-03-04 |
| NCT07223580 | A Study Of Corticosteroid On Postoperative Pain After Ureteroscopy For Urinary Calculi | Ureteroscopy | Recruiting | 2026-02-03 |
| NCT06045936 | A Study of Contralateral Limb Block | Limb Pain, Phantom | Recruiting | 2026-01-06 |
| NCT03821857 | Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease | Alzheimer Disease | Recruiting | 2025-11-24 |
Heart Disease (53) · Breast Cancer (49) · Obesity (28) · Prostate Cancer (27) · Glioma (23) · Dementia (20) · Diabetes (20) · Head & Neck Cancer (19) · Lung Cancer (19) · Heart Failure (18)