Also listed under Prostatic Diseases

ClinicalTrials.gov term: Prostatic Neoplasms

Disease landscape

Prostate Cancer clinical trials

Get alerts when Prostate Cancer trials change
Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

What changed in the last 30 days

163 trials changed in the last 30 days: 1 stopped, 82 with notable changes, 80 with minor changes only.

  1. Stopped

    HORMES · Neuromuscular ElectroStimulation in Addition to a Physical Activity Program

    Trial terminated

    Sponsor's reason: Recruitment has slowed considerably in recent months, making it particularly difficult to enroll new participants. This slowdown is partly due to recent changes in the management of prostate cancer.

    Also in this update: Primary completion date changed from estimate of Jun 2027 to Aug 4, 2026; Final enrollment: 28 participants (planned 48)

    GCS Ramsay Santé pour l'Enseignement et la RechercheNot applicable NCT05745844 Registry history of NCT05745844 on ClinicalTrials.gov (opens the registry)

    Updated

  2. Notable

    Real-World Characteristics, Treatment Patterns, and Outcomes Among mCRPC Patients Previously Treated With an Androgen Receptor Pathway Inhibitor, Taxane-Based Chemotherapy, and Lutetium-177 Vipivotide Tetraxetan

    Primary and study completion pushed from Nov 30, 2026 to May 31, 2027

    Novartis PharmaceuticalsNot specified NCT07677267 Registry history of NCT07677267 on ClinicalTrials.gov (opens the registry)

    Updated

Show 80 trials with minor changes only
  1. Minor

    RE-ENGAGE · Treatment Patterns and Factors Determining the Choice of Treatment in Canadian · Metastatic Hormone Sensitive Prostate Cancer in Routine Medical Care

    Trial completed

    Also in this update: Primary completion date changed from estimate of Dec 31, 2026 to Jun 30, 2026; Final enrollment: 477 participants (planned 700)

    BayerNot specified NCT06874114 Registry history of NCT06874114 on ClinicalTrials.gov (opens the registry)

    Updated

  2. Minor

    Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan · PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)

    Primary completion pushed from Apr 20, 2027 to Aug 2027

    Also in this update: Study completion pushed from Apr 20, 2027 to Oct 2031

    Convergent TherapeuticsPhase 2 NCT06549465 Registry history of NCT06549465 on ClinicalTrials.gov (opens the registry)

    Updated

  3. Minor

    MIDAS-SBRT · Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas in Salvage Radiotherapy Using SBRT for Prostate Cancer to Reduce Treatment Toxicity

    Primary and study completion pushed from May 1, 2034 to Oct 1, 2034

    University Health Network, TorontoPhase 2 NCT07515651 Registry history of NCT07515651 on ClinicalTrials.gov (opens the registry)

    Updated

  4. Minor
    12 trials marked Unknown by the registry's verification sweep
    1. Minor

      RAPSON · Sequencing of Radium-223 and Docetaxel in Symptomatic Bone-only Metastatic Castration-resistant Prostate Cancer

      Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting

      Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSPhase 2 NCT03230734 Registry history of NCT03230734 on ClinicalTrials.gov (opens the registry)

      Changed

    Registry verification sweep

    Changed

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-10-15 NCT07875192 Hugo™ Robotic Assisted Surgery (RAS) System in Prostatectomy Patients Treated in an ASC… Central Ohio Urology Group new
2026-10-13 NCT07869888 A Study of QLS2401 Injection in Participants With Advanced Prostate Cancer Shanghai Qilu Pharmaceutical Research and Development Center LTD new Phase 1
2026-10-13 NCT07870096 ITR-251 in Patients With Advanced Solid Tumors ITERIA BIOPHARMA, S.L. new Phase 1
2026-10-13 NCT07871435 GI-102 (CD80-IgG4 Fc-IL2v3) in Combination With Pasritamig in Patients With Metastatic… GI Innovation, Inc. new Phase 1/2
2026-10-08 NCT07866300 A Study of KMV002 in Patients With mAPMR Prostate Cancer Chimivac INC new Phase 1
2026-10-07 NCT07862582 RYZ711 Diagnostic Platform Study RayzeBio, Inc. new Phase 1/2
2026-09-28 NCT07844304 CascadeDiagnose Prostate MRI First Affiliated Hospital of Guangxi Medical University new
2026-09-24 NCT07838753 A Study Testing if Patients With Advanced Prostate Cancer Who Are Responding Well to… Kokilaben Dheerubhai Ambani Hospital and Research new Phase 2
2026-09-21 NCT07830511 RIsk aDapted Stereotactic Radiotherapy vs. standarD of Care Radiotherapy in Patients With… Robert Förster new Phase 3
2026-09-21 NCT07830212 Diagnostic Performance of ACP3-Targeted PET Imaging in Patients With Primary and… Yong He new Phase 2

Active trials by phase

Early Phase 1
44
Phase 1
205
Phase 1/2
160
Phase 2
421
Phase 2/3
32
Phase 3
169
Phase 4
30
Not charted: 1,053 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 2,114

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07569926 Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of… Blue Earth Diagnostics Recruiting 2026-10-07
NCT07848828 Autonomic and Renal Contributions to Hypertension With ADT Virginia Commonwealth University Recruiting 2026-09-30
NCT07252726 Evaluating Dose Timing (Morning vs Evening) of Endocrine-based Therapies in Metastatic… Ottawa Hospital Research Institute Recruiting 2026-07-17
NCT05348876 A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real… Bayer Recruiting 2026-07-06
NCT05803941 Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate… Novartis Pharmaceuticals Recruiting 2026-06-04
NCT06733350 Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men… Roswell Park Cancer Institute Recruiting 2026-05-14
NCT06099093 Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan Brigham and Women's Hospital Recruiting 2026-01-29
NCT04373564 Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based… Guerbet Recruiting 2026-01-22
NCT05919329 Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal… OHSU Knight Cancer Institute Recruiting 2025-10-24
NCT07001709 Determining the Effect of Abiraterone on the Metabolism of Oxycodone in Men With Prostate… Deventer Ziekenhuis Recruiting 2025-06-03
NCT05805436 Preop Laxatives in Robotic Urologic Surgery Chad R. Tracy Recruiting 2025-05-30
NCT06784986 Impact of Using the Airseal System With Ultra-low Pneumoperitoneum in Patients Undergoing… Brazilian Institute of Robotic Surgery Recruiting 2025-01-20
NCT06706921 18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy… VA Greater Los Angeles Healthcare System Recruiting 2024-11-27
NCT05629494 Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test Albany Medical College Recruiting 2024-10-18
NCT06001619 Prostate Medication, Metabolism and Gut Microbiota Turku University Hospital Recruiting 2023-08-21
NCT06908694 Investigation of GLP1-Receptor Agonists in Men With Prostate Cancer Taking Androgen… Hamilton Health Sciences Corporation Active, Not Recruiting 2026-09-14
NCT07802847 Innovative and Cooperative Pathway Integrating Oncogeriatric, Pharmaceutical and… Gustave Roussy, Cancer Campus, Grand Paris Not Yet Recruiting 2026-09-03
NCT07766122 Analysis of the Performance of PSMA Emission Tomography in Patients With Prostate Cancer… University Hospital, Toulouse Not Yet Recruiting 2026-08-14
NCT07278362 Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under… University of Miami Not Yet Recruiting 2026-07-22
NCT04549207 Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients… Ottawa Hospital Research Institute Active, Not Recruiting 2026-07-21
NCT04597125 RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs… Bayer Active, Not Recruiting 2026-07-06
NCT07677566 177Lu-PSMA-617 Combined With Darolutamide in Neoadjuvant Treatment of High-risk Localized… The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Not Yet Recruiting 2026-07-01
NCT05722925 Evaluating Fluciclovine PET in Patients With Biochemical Recurrence of Prostate Cancer… OHSU Knight Cancer Institute Active, Not Recruiting 2026-06-29
NCT05753046 Laparoscopic TAP Block During Robotic Assisted Laparoscopic Radical Prostatectomy for… Corewell Health East Enrolling by Invitation 2026-04-23
NCT05457257 Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With… AstraZeneca Active, Not Recruiting 2026-04-21

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